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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
__PClose Ups_or_ Ups_or_arrettlets 1h30_CardiopulmonaryHip FlushingBulhearted disorder, also known as angina, is a common finding in angina. It can cause chest pain, andilaprost is an angiotensin converting enzyme (AT) inhibitor. It comes in the form of cans of 100 mg tablets, which can be distributed to other areas of the body, providing a convenient and manageable option.ott 7ros 0.625 mg
  1. ott wrote:

    Hi, I've been on itraconazole for 10 years and am having a couple of episodes of angina. Are there any interactions I should be aware of with the other drugs on this list?

  2. Hi Ive been on itraconazole for 10 years and am having a couple of episodes of angina.

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Tadalafil Dosage

Cialis can be taken as needed, but it is essential to follow the recommended dosage schedule. The recommended dose of Tadalafil is 5 mg, It is taken one to two hours before sexual activity, and can last up to 36 hours. The dosage can be adjusted depending on the individual response. It is important to note that the maximum dose is 20 mg, and not more than 5 mg per day. It is best to take it at least one hour before sexual activity.

Tadalafil Side Effects

Cialis may cause side effects, but it is generally well-tolerated. Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
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  • Back pain

These side effects are usually mild and temporary. If they persist or worsen, consult your doctor immediately.

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How to use Cialis?

Take Cialis by mouth as directed by your doctor, usually as needed. You can take it with or without food, but it is important to avoid heavy meals if you take it with food. If you miss a dose, take it as soon as you remember. However, if it is close to the time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed dose.

MADALIGNANTES ISHILL, N. M. (AP) — The first big drugmaker to make a generic version of Pfizer’s erectile dysfunction drug, Cialis, will be the first to stop selling the drug. The new, generic version of Viagra, the world’s best-known erectile dysfunction drug, will be marketed to men with ED and a lower risk of heart attack and stroke.

“We believe that men with ED can feel their best and most satisfying sexual life,” said Dr. Mark C. Henry, the head of drug strategy at Pfizer Inc.’s drugmaker, which makes Viagra, and co-CEO William Surowitz said in a statement.

Viagra was Pfizer’s first-ever drug to sell for erectile dysfunction, the drug’s active ingredient, sildenafil citrate. Viagra can help men get and keep an erection, but men who have a weak or blocked erection might not be able to get it, said C. J. Haddox, vice president of marketing and sales at Pfizer. Viagra helps men with erectile dysfunction with a blood flow to the penis, he said.

Viagra sales reached $1 billion last year, with sales reaching $2.5 billion in the U. S., the company said.

Originally Published: September 27, 2017 at 12:00 AM EDT

Pfizer Inc. (NYSE: PFE) has just approved a deal with rival CVS Corp. to sell Cialis, the world’s best-selling erectile dysfunction drug, to distributors in the U. S. The drugmaker, which makes the brand name Viagra, said the deal would bring the amount of money it would earn from selling Viagra to consumers in the U. to as much as $1 billion each.

CVS and its distributor will receive a share of the profits, Pfizer said. But the company said sales would be limited to about $300 million a year. Pfizer said it was considering a lower price for Viagra, but the drugmaker said it could not be certain how much it will receive from the sale.

“There’s been some criticism of the way that CVS has marketed products and the way it has marketed products,” Henry said in a statement.

Cialis has traditionally been used as a drug that needs to be prescribed and taken only on an as-needed basis. That is, you will be given a modest number of tablets to ingest in advance of having sexual intercourse within the following hours. This type of as-needed Cialis dose has been used since it was introduced to the market as a prescription medication for men with erectile dysfunction and wanting to have sex on a semi-frequent basis.

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Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

  • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
  • Your doctor may recommend taking generic Cialis regularly, once a day.

Follow your doctors instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

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Take tadalafil generic as prescribed by your doctor. Be sure to discuss all medications, supplements, and alcohol you are currently taking with your doctor before starting treatment.

For the best effect, take tadalafil generic regularly to get the best results. If you miss a dose, take it as soon as you remember. However, if you are not sure when you took the doses, your doctor may start you up with a new dose of tadalafil generic once per day.

If you are taking brand-name Tadalafil generic, discuss your contraception with your doctor.

AthleticAnalyst, Clinical StudiesCialis Patient Tips:1. Follow a consistent schedule to maintain stable erections during daily use. Tadalafil may take effect as soon as 30 minutes after ingestion and can remain effective for up to 36 hours after treatment discontinuation. Avoid consuming alcohol while taking tadalafil generic, as it may increase the risk of side effects. 2. Avoid grapefruit juice while taking tadalafil generic, as it may interact with grapefruit juice and potentially reduce its effectiveness. 3. Consult your healthcare provider for personalized advice regarding dosage and treatment duration.

Source:

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